Decoding Human Blood Groups

Most people are familiar with the ABO and Rh blood groups. However, human blood types are more diverse and complex than these two classifications suggest. ABO and Rh are only 2 of the 48 human blood group systems identified to date.

In addition, few people understand how these systems generate diverse human blood types.

Furthermore, the Internet is rife with myths claiming that individuals with particular blood types should adopt specific diets to avoid gaining weight. Such misconceptions reveal how little is generally understood about the importance of blood groups and their relevance to human health, whether in clinical practice, normal human physiology, or the associations between blood types and disease susceptibility.

Decoding Human Blood Groups was written by a Professor of Biochemical Sciences at National Taiwan University, after 3 decades of research on human blood type genes. A long devoted to the field of basic science, the author explores the study of human blood groups, an area closely intertwined with clinical medicine that he describes as a treasure trove. Drawing on his expertise in biochemistry and molecular biology, the author offers readers a comprehensive account of blood groups, the most prominent and clinically significant form of human polymorphism.

This book recounts the history of blood group discoveries, examines several major blood group systems, and discusses blood types that show distinctive associations within Taiwan. It clarifies the meaning of the term “blood type” by explaining how variations in the antigenic structures on the surface of red blood cells, in biochemical synthesis pathways, and in genetic mutations produce differences between individuals.

Additionally, the author emphasizes the importance of blood groups in transfusion safety and other areas of clinical medicine, their contribution to normal physiological functions, and their links to certain diseases. Notably, the book incorporates findings from the author’s research as well as studies conducted by other researchers in Taiwan. In addition to a popular science book for general readers, the book offers a rich repository of historical insight and scientific knowledge for students and professionals in biochemistry, molecular biology, blood group research, and transfusion medicine.